Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Ammonium chloride ingestion attenuates exercise-induced mRNA levels in human muscle Research output : Contribution to journal › Journal article › Research › peer-review Presentation Gives off irritating or toxic fumes (or gases) in a fire. If you take diphenhydramine and ammonium chloride on a regular basis, take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. (USCG, 1999) Reactivity Profile. Use … Case Report. cause serious harm. May be harmful if inhaled. Ammonium Chloride has no known severe interactions with other drugs. No Results . Materials and methods. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. Ingestion of ammonium hydroxide, while uncommon, results in corrosive damage to the mouth, throat, and stomach. Ammonium Chloride Salmiac 12125-02-9 NH 4Cl ≥ 99.5 Trade Secret Statement: Not applicable. In case of fire in the surroundings, use appropriate extinguishing media. Water spray may We present a case of an intentional ingestion of a dilute ammonium chloride solution resulting in significant morbidity. Moderate interactions of ammonium chloride include: amphetamine; dextroamphetamine; dichlorphenamide; lisdexamfetamine; methamphetamine; methylenedioxymethamphetamine; Mild interactions of ammonium chloride include: spironolactone ; This document does not contain all possible interactions. This study examined the effects of NH 4 Cl ingestion on phosphocreatine (PCr) metabolism during 9 min of moderate- (MOD) and heavy- (HVY) intensity constant-load isotonic plantar-flexion exercise. How Many Meq Of Ammonium Chloride Are Present In A 20-ml Vial ?-apatient Is Given 125mg Phenytoin Sodium(c15h11n2nao2—m.w.274)three Times A Day. Sore throat. SIDS Initial Assessment Report For SIAM 17 - Ammonium Chloride (12125-02-9) Author: OECD SIDS Year: 2004 Bibliographic source: OECD- submitted on Janaury 30th 2004. This website and underlying databases are maintained and updated by Pesticide Action Network North America (PAN). Mixtures of about 16% to 25% (by volume) ammonia gas in air are flammable. People with impaired respiratory functions, such as those with emphysema much incur further damage if the chemical is inhaled. The symptoms and treatment for ammonia exposure are similar to those for ammonium hydroxide. It is also harmful by inhalation or skin absorption. Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire. Other products may also contain ammonium hydroxide and ammonia. Effect of sodium bicarbonate and ammonium chloride ingestion in experimental gentamicin nephrotoxicity in rats. Call a physician if symptoms occur. Ammonium chloride fume may cause an asthma-like allergy. Effects of ammonium chloride ingestion on phosphocreatine metabolism during moderate- and heavy-intensity plantar-flexion exercise | springermedizin.de Skip to main content At fire temperatures ammonium chloride begins to corrode metals and may dissociate into ammonia and hydrogen chloride. Note to physician: Symptoms : Overexposure may cause:, vomiting, lethargy, confusion, hyperventilation, nausea, headache. Elliott WC, Parker RA, Houghton DC, Gilbert DN, Porter GA, DeFehr J, Bennett WM. A complicated hospitalization following dilute ammonium chloride ingestion Journal of Medical Toxicology , Dec 2009 Kendra Hammond MD , Tiffany Graybill , Susannah E. Spiess MD , Jenny Lu MD , Jerrold B. Leikin MD Explosion: Not considered to be an explosion hazard. Identification . The EU classification refers to a group of substances known as quaternary ammonium compounds, benzyl C8-18-alkyldimethyl chlorides. 77, No. EXPOSURE: Exposure to didecyl dimethyl ammonium chloride is most often from skin or eye contact, but can also include inhalation or ingestion. May cause irritation of the digestive tract. 1.1. Contact with eyes or skin causes irritation. It is also used as a refrigerant gas, and in the manufacture … Other CAS RN: 8001-54-5; Other UN numbers are possible, depending on manufacturers´classifications. Ingestion. 58 / Monday, March 26, 2012 / Rules and Regulations Issue date: 07/24/2006 Revision date: 05/21/2020 Supersedes: 11/02/2016 Version: 2.2 05/21/2020 EN (English US) Page 1 SECTION 1: Identification . Do not take 2 doses at the same time or extra doses. Inhalation of ammonium chloride fumes can result in irritation of the nose, throat and lungs, including coughing and a sore throat. (NTP, 1992) Reactivity Profile. Ammonium Chloride Safety Data Sheet according to Federal Register / Vol. Benzalkonium chloride itself is a mixture of very similar substances with different chain length and molecular mass. Chloride content— Transfer an accurately measured volume of Injection,evaporated,if necessary,equivalent to about 2g of ammonium chloride,to a 200-mLvolumetric flask,dilute with water to volume,and mix.Transfer 10.0mLof this solution to a conical flask,add 10mLof glacial acetic acid,75mLof methanol,and 0.5mLof eosin Y TS.Titrate,with shaking,with 0.1Nsilver nitrate VSto a pink … We present a case of an intentional ingestion of a dilute ammonium chloride solution resulting in significant morbidity. It is an irritant of the skin, eyes, mucous membranes, and upper respiratory tract. Question: - Ammonium Chloride Injection Contains 267.5 Mg Of Nh4cl (m.w. ACUTE/CHRONIC HAZARDS: This compound is highly toxic by ingestion. It should be used with caution in patients with high total CO2 and buffer base secondary to primary respiratory acidosis. Therefore, before using this … 53.5) Per Milliliter. Test guideline Qualifier: equivalent or similar to Guideline: OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Deviations: yes Remarks: (reduced reporting, only 1000 PCE scored for … Benzalkonium chloride (BAK), otherwise known as alkyl dimethyl benzyl ammonium chloride, is a toxic chemical used in cosmetics. Ingestion: Harmful if swallowed. It is mainly used as fertilizer and a flavouring agent in some types of liquorice. AMMONIUM CHLORIDE: ICSC: 1051: Sal ammoniac: December 2000: CAS #: 12125-02-9 EC Number: 235-186-4 ACUTE HAZARDS PREVENTION FIRE FIGHTING; FIRE & EXPLOSION: Not combustible. Ammonia alone (not ammonium hydroxide) can be found in many household items such as detergents, stain removers, bleaches, and dyes. Ingestion: Rinse mouth. Next: Interactions. Acidic inorganic salts, such as ZINC AMMONIUM CHLORIDE, are generally soluble in water. Ammonium hydroxide can also release ammonia gas into the air. Many times diphenhydramine and ammonium chloride is taken on an as needed basis. May cause systemic toxicity with acidosis. Fire-fighting measures. Ingestion of ammonia does not normally result in systemic poisoning. On ingestion: Rinse mouth immediately and then drink plenty of water, seek medical attention. May cause systemic toxicity with acidosis. They react as acids to neutralize bases. Ammonia is manufactured by reacting hydrogen with nitrogen. Ingestion can cause irritation or corrosion of the alimentary tract. Enter a drug name and ammonium chloride. Didecyl dimethyl ammonium chloride is registered for these antimicrobial uses by the U.S. EPA Office of Pesticide Programs. Chloride content— Transfer an accurately measured volume of Injection, evaporated, if necessary, equivalent to about 2 g of ammonium chloride, to a 200-mL volumetric flask, dilute with water to volume, and mix. Ammonium Hydroxide Poisoning is caused by the ingestion, inhalation, or exposure of skin to ammonium hydroxide and ammonium hydroxide based products; This intake could be accidental, or in some cases intentional, to bring self-harm; Ammonium hydroxide is a toxic substance that is found in a variety of cleaning solutions, cosmetics, and cements Product form : Substance Substance name : Ammonium Chloride CAS-No. Participants ingested either ammonium chloride (0.15 g.kg-1, ACID) or placebo (0.15 g.kg-1, PLA) in four doses during the 24 h prior to the trial day. When heated to decomposition this chemical emits very toxic fumes of carbon monoxide, carbon dioxide, nitrogen oxides and hydrogen chloride gas. Interaction Checker. Chloride content— Transfer an accurately measured volume of Injection, evaporated, if necessary, equivalent to about 2 g of ammonium chloride, to a 200-mL volumetric flask, dilute with water to volume, and mix. Sources/Uses. The control group contained 20 animals and the test group contained 10 animals. If not breathing, give artificial respiration. A 60-year-old woman with bipolar disorder presented one hour after an intentional ingestion of approximately 15 fluid ounces (500 mL) of an algae and odor humidifier treatment containing a total of 2.25% ethyl ammonium chloride. First Aid Procedures: Inhalation: Move to fresh air. About 80% of the ammonia produced is used in fertilizers. Alkyl* dimethyl benzyl ammonium chloride *(58%C14, 28%C16, 14%C12) - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information: Note: See Working with the Information on this Page section below for important notes about this data. Ingestion of the chemical could result in serious negative health consequences, including death. Ammonium Chloride Ingestion Attenuates Exercise-Induced mRNA Levels in Human Muscle PLOS ONE , Dec 2019 Johann Edge , Toby Mündel , Henriette Pilegaard , Emma Hawke , Murray Leikis , Nicolas Lopez-Villalobos , Rodrigo S. F. Oliveira , David J. Bishop Benzalkonium chloride (BZK, BKC, BAK, BAC), also known as alkyldimethylbenzylammonium chloride (ADBAC) and by the trade name Zephiran, is a type of cationic surfactant.It is an organic salt classified as a quaternary ammonium compound.ADBACs have three main categories of use: as a biocide, a cationic surfactant, and a phase transfer agent. In a dermal sensitization study with ammonium chloride (99.1% pure), 8 weeks old guinea pigs [Pirbright-White (Hoe: DHPK (SPFLac))] were tested according to EPA 540/9-82-025 (November 1982, revised at November 1984), a method comparable to OECD TG 406 (Hoechst, 1986). It is a antimicrobial agent, deodorant, surfactant, and a preservative. Abstract. Ammonium chloride Section 1 ­ Chemical Product and Company Identification ... Ingestion:Harmful if swallowed. SYMPTOMS PREVENTION FIRST AID; Inhalation: Cough. When didecyl dimethyl ammonium chloride is released to the environment, it will absorb to surfaces. Inhalation: If heated, dust or fume may cause respiratory tract irritation. Ammonium chloride ingestion attenuates exercise-induced mRNA levels in human muscle Edge, Johann; Muendel, Toby; Pilegaard, Henriette; Hawke, Emma; Leikis, Murray; Lopez- Healthy young adult male subjects (n = 8) completed both a control (CON) and NH 4 Cl ingestion (ACID) trial.Phosphorus-31 magnetic resonance spectroscopy was used to monitor changes … 103 is the average normal serum chloride concentration (mEq/L) and 0.2 L/kg is the estimated chloride volume of distribution. mEq of chloride ion (as ammonium chloride-NH4Cl) = [0.2 L/kg X BW (kg)] X [103 - observed serum chloride]; administer 50% of dose over 12 hr and reevaluate. May cause irritation of the digestive tract. If breathing is difficult, give oxygen. Benzalkonium chloride has repeatedly demonstrated its toxic characteristics in laboratory, experimental, and clinical studies. 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